Background

Syngenta is seeking technologies capable of precisely inserting a DNA fragment into plant genomes. Solutions with carrying capacity for cargo greater than 10 kilobase (kb) are of particular interest, as well as techniques that improve insertion efficiency.

As a leader in agricultural technologies, Syngenta employs science-based innovations that can transform food security and sustainability. Syngenta scientists are seeking novel or reimagined technologies capable of inserting a DNA fragment >10kb into a genome. Ideal solutions will have insertion efficiency equivalent to or exceeding that of Cre-Lox recombinase technology to support more effective genetic transformation and editing.

Solutions must be tested in eukaryotes, come from a known source organism or synthetic system, and must not be mammalian or human pathogen derived. Early-stage research is also of interest, particularly with in vivo data to support efficacy in eukaryotes. Syngenta is open to various partnership types, including joint research & development and technology licensing.

Ideal submissions will include an overview or reference to the methodology used for data collection, particularly molecular analysis.