Previous challenges
Escaping fluorine dependency in agrochemical design
"Better understanding how fluorine substituents impact the biokinetic profile of a molecule will help us discover the next generation of agrochemicals less dependent on fluorination for their in vivo performance."
Vlad Pascanu, Principal Scientist Crop Protection Research Chemistry, Syngenta
The Challenge
This challenge focused on identifying organizations with capabilities, tools, data and/or platforms that could help us generate robust models to understand how we can rationally replace fluorinated substituents in our molecules without adversely impacting bioactivity.
We knew it was a difficult and complex challenge, so we broke it down into several workstreams.
We received and have evaluated an encouraging number of submissions from both academia and industry and are exploring the next steps for progressing our collaborations in this space.
Moving forward
While this challenge is now closed, our innovation in this space continues. If you have novel ideas or approaches that you think will be of interest to us, we would still be interested to hear from you.